The 4th International Smoke Symposium (ISS4) will be held at the Leigh Perkins Conservation Education Center in Tallahassee, Florida, March 23-27, 2026. ISS4 will bring together researchers from the atmospheric sciences, the ecological sciences, health sciences, mathematicians, computer sciences, climatologists, social scientists, and others to discuss the complex issues of smoke and identify knowledge gaps and opportunities for innovation and development.